Exposure of Mycobacterium tuberculosis to human alveolar lining fluid shows temporal and strain-specific adaptation to the lung environment
Anna Allué‐Guardia, Andreu Garcia‐Vilanova, Alyssa Schami…·Jordi Bertran Torrelles
This study exposes M.tb strains to human alveolar lining fluid and finds strain-specific and time-dependent gene expression changes, particularly in lipid metabolism and cholesterol degradation.