Author

Joby Cole

Royal Hallamshire HospitalORCID 0000-0002-5258-5835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

David Harold DockrelliD· 2 shared Mark J. DickmaniD· 2 shared Adrienn AngyaliD· 1 shared Allan M. Carrillo‐BaltodanoiD· 1 shared Andy S LawiD· 1 shared Bo WangiD· 1 shared Clark D RusselliD· 1 shared Francisco M. Martín-ZamoraiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

David Harold DockrellORCID

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3 papers

Recent·Most cited

Evolutionary BiologyGenome biologyPeer-reviewedJun 10, 2025

The evolution and developmental dynamics of histone-based chromatin regulation in Annelida

Francisco M. Martín-Zamora, Joby Cole, Rory D. Donnellan…·José María Martín-Durán

This study investigates histone-based chromatin regulation in Annelida using multi-omics approaches, revealing lineage-specific effects on histone repertoires and functional implications of histone variants.

2 citations

non-human primateproteomics

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BioinformaticsBioinformaticsPeer-reviewedSep 12, 2022

Systematic comparison of ranking aggregation methods for gene lists in experimental results

Bo Wang, Andy S Law, Tim W. Regan…·John Kenneth Baillie

This study compares ranking aggregation methods for gene lists using simulated and real data to evaluate their performance in meta-analyses.

18 citations

humanvirus

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Molecular BiologyFrontiers in ImmunologyPeer-reviewedMay 11, 2021

Pneumolysin is responsible for differential gene expression and modifications in the epigenetic landscape of primary monocyte derived macrophages.

Joby Cole, Adrienn Angyal, Richard David Emes…·David Harold Dockrell

This study shows pneumolysin alters gene expression and histone modifications in macrophages, dampening innate immune responses through epigenetic mechanisms.

14 citations

humanbulk RNA-seq

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