Joy Scaria

This study shows that an engineered probiotic expressing an endolysin reduces Clostridioides difficile infection in mice with disrupted microbiota.

This study identifies 3,4-dihydroxybenzoic acid (DHBA), a rutin metabolite, as a potent antibiotic potentiator that restores susceptibility in XDR Gram-negative pathogens through a system-wide genetic susceptibility signature.

This study investigates how nasal microbiota colonization in germ-free pigs affects immune responses and gut-lung axis interactions, showing antibiotic disruption of microbial diversity and immune gene expression.

The paper identifies key microbial interactions and metabolic pathways that confer resistance to C. difficile invasion using synthetic and clinical communities.

This study uses C. elegans to screen human gut microbiota for colonization and resistance against C. difficile, finding 46% colonization success and 50% in vivo inhibition of C. difficile.

This study analyzes the population genomics of Salmonella enterica Dublin, finding that geographical regions shape its genomic structure and antibiotic resistance profiles.