Mervyn P.H. Mol

This study shows that endothelial cells enhance doxorubicin-induced cardiotoxicity in co-cultures with cardiomyocytes, challenging the focus on cardiomyocytes alone.

This study develops scalable 3D cardiac microtissues for high-throughput drug screening, showing reproducible drug responses and identifying 17 drugs that rescue arrhythmic phenotypes.

The paper shows that a gain of chromosome 1q31.3 in human iPSCs leads to increased TNNT2 expression and altered contraction in derived cardiomyocytes.