Author

Loukia Yiangou

Leiden University Medical CenterORCID 0000-0003-1477-005XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Christine L. MummeryiD· 2 shared Mervyn P.H. MoliD· 2 shared Milena BelliniD· 2 shared Richard P. DavisiD· 2 shared Anna OsnatoiD· 1 shared Benjamin B. JohnsoniD· 1 shared Benoît Samson-Couterie· 1 shared Daniel Ortmann· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

Christine L. MummeryORCID

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3 papers

Recent·Most cited

Cell BiologyTrends in biotechnologyPeer-reviewedDec 18, 2025

Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening

Tessa de Korte, Benjamin B. Johnson, Georgios Kosmidis…·Richard P. Davis

This study develops scalable 3D cardiac microtissues for high-throughput drug screening, showing reproducible drug responses and identifying 17 drugs that rescue arrhythmic phenotypes.

6 citations

humanorganoid / primary culture

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Cell BiologybioRxivPreprintDec 11, 2023

Gain of chromosome region 1q31.3 in human iPSCs confers growth advantage and alters contraction in derivative cardiomyocytes

Karina O. Brandão, Viviana Meraviglia, Daniela C. F. Salvatori…·Richard P. Davis

The paper shows that a gain of chromosome 1q31.3 in human iPSCs leads to increased TNNT2 expression and altered contraction in derived cardiomyocytes.

1 citation

humanbulk RNA-seq

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Developmental BiologyJournal of Biological ChemistryPeer-reviewedSep 12, 2019

Cell cycle regulators control mesoderm specification in human pluripotent stem cells

Loukia Yiangou, Rodrigo A. Grandy, Anna Osnato…·Ludovic Vallier

This study investigates how cell cycle regulators influence mesoderm specification in human pluripotent stem cells, finding that CDKs and pRb phosphorylation are context-dependent for efficient mesoderm formation.

25 citations

humanexperimental assay

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