Author

Paolo Conflitti

Università della Svizzera italianaORCID 0000-0002-5440-6167Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 2 Approach:mechanistic / dynamical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Vittorio LimongelliiD· 2 shared Luciana MarinelliiD· 1 shared Stefano RanioloiD· 1 shared Vince Bart CardenasiD· 1 shared Vincenzo Maria D’AmoreiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Vittorio LimongelliORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 31, 2025

Beyond the 1:1 Ligand-Protein Paradigm: An In Silico Assay for Competitive Ligand Binding

Vince Bart Cardenas, Stefano Raniolo, Paolo Conflitti, Vittorio Limongelli

The paper introduces a coarse-grained MD approach to simulate competitive ligand binding at the adenosine A2A receptor, revealing cooperative mechanisms in ligand competition.

1 citation

structural biologydeep learning

𝕏 PostBluesky

BiophysicsChemPeer-reviewedSep 9, 2024

Minute-timescale simulations of G Protein Coupled Receptor A2A activation mechanism reveal a receptor pseudo-active state

Vincenzo Maria D’Amore, Paolo Conflitti, Luciana Marinelli, Vittorio Limongelli

This study uses molecular dynamics simulations to reveal a pseudo-active state in the A2A receptor, providing insights into its activation mechanism and signaling pathways.

27 citations

mechanistic / dynamical modelchromatin & epigenetic regulation

𝕏 PostBluesky