Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing
Audra L. Amasino, Shalini Gupta, Larry J. Friedman…·Stephen P. Bell
The paper investigates how ORC phosphorylation inhibits helicase loading by preventing Mcm2-7 ring closure in budding yeast.
17 citations