Molecular BiologybioRxivPreprint
Targeting the Mitochondrial Phenotype in Cockayne Syndrome Patient Cells: From Bioenergetic Fragility to Pharmacologic Rescue
Melis Kose, Elizabeth M. McCormick, Kelsey Keith…·Marni J. Falk
This study identifies five compounds that improve mitochondrial function and survival in Cockayne syndrome patient fibroblasts by targeting oxidative stress, autophagy, and cellular resilience.
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