Cell BiologybioRxivPreprint
Membrane potential and feedback dynamics regulate CatSper-mediated progesterone signaling in human sperm
Michelina Kierzek, Dmitry Fridman, Cristina Biagioni…·Timo Strünker
This study investigates how progesterone regulates membrane potential and Ca2+ signaling in human sperm through CatSper and Slo3 channels, revealing feedback mechanisms that control depolarization and repolarization.
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