GeneticsbioRxivPreprint
Cellular morphology emerges from polygenic, distributed transcriptional variation
Seyedeh Zahra Paylakhi, Rafael Geurgas, Antionette Yasko…·Matthew Tegtmeyer
The paper shows cellular morphology is a polygenic trait by integrating perturbation data, genetic variation, and cross-modal modeling to predict morphology from gene expression.
DOI 10.64898/2026.03.12.711281