Author

Erich Hellemann

University of PittsburghORCID 0000-0002-5565-8614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Jacob D. DurrantiD· 2 shared Amanda K. LukensiD· 1 shared Andrea L. Cheung· 1 shared Case W. McNamaraiD· 1 shared Dyann F. WirthiD· 1 shared Eddy Vigil· 1 shared Elizabeth A. WinzeleriD· 1 shared Emmanuelle V. LeBlanciD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Jacob D. DurrantORCID

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2 papers

Recent·Most cited

BioinformaticsJournal of Chemical Theory and ComputationPeer-reviewedAug 16, 2023

Worth the weight: Sub-Pocket EXplorer (SubPEx), a weighted-ensemble method to enhance binding-pocket conformational sampling

Erich Hellemann, Jacob D. Durrant

SubPEx improves binding-pocket conformational sampling using weighted ensemble methods, demonstrating effectiveness on drug discovery targets.

11 citations

protein structurestatistical model

𝕏 PostBluesky

GeneticsbioRxivPreprintFeb 17, 2021

Defining the Yeast Resistome through in vitro Evolution and Whole Genome Sequencing

Sabine Ottilie, Madeline R. Luth, Erich Hellemann…·Elizabeth A. Winzeler

The paper identifies genetic determinants of chemical resistance in yeast using in vitro evolution and whole genome sequencing, revealing key transcription factors involved in drug resistance.

4 citations

yeastwhole-genome sequencing

𝕏 PostBluesky