Rosela Golloshi

The paper develops a polymer model integrating super-resolution imaging and epigenomic sequencing to show how epigenetic reactions shape 4D chromatin organization and influence gene expression and metastatic potential.

The paper identifies 3D genome architecture changes in melanoma cells before and after constricted migration, linking them to migration ability and cell fate changes.

This study shows that constricted migration in cancer cells leads to stable 3D genome structure changes associated with increased migration efficiency and altered gene expression.

The paper investigates how genome structure responds to nuclear swelling, finding that global topology remains elastic and robust despite dramatic volume changes.

This study examines how DNA damage and repair affect 3D genome organization using Hi-C in different cell types, finding cell-type-specific changes and TAD boundary strengthening in repair-proficient cells.

This paper evaluates Hi-C protocol modifications and identifies factors affecting data quality and DNA loss in Hi-C experiments.