Mia S. Frier

This paper identifies VINE as a dual Rab regulator that activates Ypt10 and suppresses Vps21 to control late endosomal Rab signaling in yeast.

The paper identifies VINE, a VPS9-family GEF complex, as a regulator of Rab5 inactivation through phosphatase recruitment and GAP-mediated dephosphorylation.

This study identifies N-terminal signals in Vin1 and Vps5 that guide the formation of specific endosomal coat complexes in yeast.