Author

Chaoqi Chen

Chinese Academy of SciencesORCID 0000-0002-5645-7718Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Fanglin LiiD· 1 shared Fengru Qiu· 1 shared Fengyu DuiD· 1 shared Likun GongiD· 1 shared Liying CheniD· 1 shared Rong Zhang· 1 shared Rongchen Liu· 1 shared Runqiu CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Fanglin LiORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJan 21, 2026

CTLA-4 inhibitors drive colitis through metabolic reprogramming-mediated Treg/Th17 imbalance

Zhiying Li, Shanna Wu, Rongchen Liu…·Yiru Long

This study identifies metabolic reprogramming as a mechanism by which CTLA-4 inhibitors cause colitis, showing that metformin can alleviate this toxicity without affecting antitumor efficacy.

DOI 10.64898/2026.01.20.700699

mousebulk RNA-seq

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