Author

Fernando Gómez-Herreros

Instituto de Biomedicina de SevillaORCID 0000-0002-5693-3489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Diana Rubio-ContrerasiD· 2 shared Anne‐Claude GingrasiD· 1 shared Arne Nedergaard KousholtiD· 1 shared Atina G. CotéiD· 1 shared Binghui SheniD· 1 shared Carmen Angulo-Jiménez· 1 shared Carmen Jordán-Pérez· 1 shared Daniel Delgado‐BellidoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Diana Rubio-ContrerasORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 9, 2026

EXO1 Facilitates MiDAS and Prevents Genome Instability and Cell Death in Ewing Sarcoma

Joaquín Olmedo-Pelayo, Laura Lobo-Selma, Daniel Delgado‐Bellido…·Enrique de Álava

This study identifies EXO1 as essential for Ewing sarcoma cell survival and shows its role in preventing genome instability and cell death by facilitating MiDAS.

DOI 10.64898/2026.06.05.730187

humanexperimental assay

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GeneticsCell Death and DiseasePeer-reviewedNov 28, 2025

SCAN1 mutant TDP1 blocks the repair of DSB induced by TOP1 activity during gene transcription and promotes genome reorganisations and cell death in quiescent cells

Diana Rubio-Contreras, Daniel Hidalgo-García, Carmen Angulo-Jiménez…·Fernando Gómez-Herreros

This study shows that the SCAN1 mutation H493R in TDP1 blocks repair of TOP1-induced DSBs in quiescent cells, leading to genome instability and cell death.

DOI 10.1038/s41419-025-08085-y

humanexperimental assay

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Molecular BiologybioRxivPreprintSep 23, 2022

Genome-scale mapping of DNA damage suppressors identifies GNB1L as essential for ATM and ATR biogenesis

Yichao Zhao, Daniel R. Tabet, Diana Rubio-Contreras…·Daniel Durocher

The paper identifies 160 genes that suppress DNA damage in human cells through CRISPR/Cas9 screens, highlighting GNB1L's role in ATR biogenesis and its link to neuropsychiatric disorders.

DOI 10.1101/2022.09.23.508845

humanCRISPR screen

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