Neha Neha

This study shows Guggulsterone induces apoptosis in prostate cancer cells by increasing NKX3.1 expression and stabilizing its mRNA and protein, suggesting it as a potential chemoprevention target.

The paper identifies G-quadruplex forming sequences in the PRCC-TFE3 fusion gene and demonstrates their stabilization by pyridostatin, suggesting potential as a therapeutic target for tRCC.

This paper uses computational methods to analyze how the Omicron variant's mutations affect its binding to ACE2 and antibodies compared to Delta and wild-type SARS-CoV-2.

The paper analyzes SARS-CoV-2 RBD variants using molecular dynamics to assess their impact on vaccine efficacy and ACE2/antibody binding.