Author

Chen Zhang

Zhejiang UniversityORCID 0000-0002-5733-7574Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Chen Zhang7 papers · Capital Medical University

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Xin Zhiguo LiiD· 2 shared Banghua HeiD· 1 shared Chenyu Pei· 1 shared Guangnan Li· 1 shared Haifeng ZhangiD· 1 shared Hongyan CuiiD· 1 shared Huali Luo· 1 shared Jiaoyan MaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Xin Zhiguo LiORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintFeb 23, 2026

Type 2 diabetes amplifies environmental Pb toxicity and intergenerational risk

Chen Zhang, Xiaoping Xia, Chen Zhang…·Xin Zhiguo Li

This study shows that type 2 diabetes increases susceptibility to lead toxicity, leading to organ damage and intergenerational health risks.

1 citation

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Cell BiologybioRxivPreprintSep 17, 2025

DNA damage hypersensitivity in chicken primordial germ cells limits CRISPR-Cas9 editing and supports an shRNA-based screening approach

Chen Zhang, Xin Zhiguo Li

The paper identifies DNA damage hypersensitivity in chicken PGCs as a barrier to CRISPR-Cas9 editing and demonstrates shRNA as a viable alternative for functional screening.

DOI 10.1101/2025.09.17.676926

chicken / avianCRISPR screen

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