Henning Seedorf

The paper analyzes adhesin-like proteins (ALPs) in Methanobacteriales species to understand their role in gut microbiota interactions and species-specific adaptations.

PRISM enables sequence-independent, one-shot fine-tuning for simultaneous protein domain segmentation and classification, improving accuracy for complex and novel architectures.

The paper identifies GuFi phages as prevalent gut viral families using long-read sequencing and shows their broad host ranges and underappreciated impact on the microbiome.

This paper evaluates a high-throughput single-cell dispensing platform for isolating Bifidobacterium strains from fecal samples, demonstrating its effectiveness in recovering diverse, novel bacterial isolates.

This study identifies bacteriocin genes co-occurring with antibiotic resistance and virulence factors in gut E. coli, highlighting their role in microbial dynamics and resistance dissemination.

This study compares tet(X4)-containing contigs from metagenomic data with plasmid sequences from isolates in a healthy cohort, finding high similarity and co-occurrence of resistance genes.

The paper investigates how heat stress affects immune responses and skin microbiota in farmed fish in Singapore's recirculating aquaculture system.

The paper uses long-read and Hi-C technologies to analyze gut microbiomes from Southeast Asians, revealing novel species, improved references, and uncharacterized biosynthetic gene clusters.