Luis M. Schang

This paper identifies the antiviral moieties in EGCG and develops small molecule inhibitors with broad-spectrum antiviral activity against viruses attaching to glycosaminoglycans or sialylated glycans.

The paper predicts 3D structures of viral-host protein interactions and identifies evolutionary patterns and functional mechanisms underlying viral pathogenesis.

This study shows BAF chromatin remodeling complexes inhibit HSV-1 immediate-early and early transcription but not late transcription or DNA replication during lytic infection.

This study identifies H2A.B as a histone variant enriched in dynamically chromatinized HSV-1 lytic chromatin, suggesting its role in promoting transcriptional activity.