Carla Salomo-Coll

The paper introduces a pipeline for single-cell proteomics analysis that addresses challenges in data processing and annotation using context-aware methods and large language models.

This study shows that proteostatic failure in ER-phagy, driven by Kras, leads to protein aggregates that prime acinar-ductal metaplasia and pancreatic cancer.

The paper shows chronic lysosome damage from Palbociclib treatment in cancer cells triggers interferon responses via mitochondrial nucleic acid release, dependent on lysosome-mitochondrion contacts.