Molecular BiologyNucleic Acids ResearchPeer-reviewed
Spliceosomal mutations decouple 3' splice site fidelity from cellular fitness
Kevin R. Roy, Jason Gabunilas, Dean Neutel…·Guillaume Chanfreau
This study shows that inactivating Prp18p leads to global activation of alternative 3' splice sites with divergent sequences, without affecting cellular fitness.
11 citations