Author

Naiduwadura Ivon Upekala De Silva

University of Alabama at BirminghamORCID 0000-0002-5937-0271Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Jun ZhangiD· 2 shared Talia FargasoniD· 2 shared Trenton M. PauliD· 2 shared Zihan ZhangiD· 2 shared Erin PowelliD· 1 shared Nathan Lehman· 1 shared Peter E. Prevelige· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

Jun ZhangORCID

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2 papers

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedFeb 19, 2025

Controlled by disorder: phosphorylation modulates SRSF1 domain availability for spliceosome maturation

Talia Fargason, Erin Powell, Naiduwadura Ivon Upekala De Silva…·Jun Zhang

This study shows phosphorylation of SRSF1's RS domain modulates its interactions with RRM1 and RNA, affecting spliceosome maturation and phase separation.

8 citations

humanproteomics

𝕏 PostBluesky

BiophysicsBiophysical JournalPeer-reviewedFeb 1, 2024

Unearthing SRSF1's Novel Function in Binding and Unfolding of RNA G-Quadruplexes

Naiduwadura Ivon Upekala De Silva, Talia Fargason, Trenton M. Paul…·Jun Zhang

This study identifies SRSF1's novel ability to bind and unfold RNA G-quadruplexes, revealing new roles for its RS domain in RNA regulation.

DOI 10.1016/j.bpj.2023.11.1956

humanproteomics

𝕏 PostBluesky