Arunasree Marasanapalli Kalle

This study identifies novel HDAC11 inhibitors through in silico and in vitro approaches, showing they reduce breast cancer cell viability and induce apoptosis.

This study identifies HDAC6's role in regulating MLLT3 levels via Hsp90 activation during myeloid differentiation, showing differential effects on MK and macrophage fate compared to monocytes.

This study investigates how two HDAC inhibitors, sodium butyrate and Trichostatin A, induce distinct DNA methylation changes and affect X-chromosome inactivation in breast cancer cells.

This study shows HDAC6 promotes PMA-induced megakaryocyte differentiation in K562 cells by increasing ROS via NOX4 and repressing the erythroid marker GYPA.