GeneticsFrontiers in GeneticsPeer-reviewed
A simple approximation to bias in gene-environment interaction estimates when a case might not be the case
Iryna V. Lobach, Inyoung Kim, Alexander V. Alekseyenko…·Li Zhang
The paper derives a simple approximation to bias in gene-environment interaction estimates when clinically diagnosed cases may include a nuisance pathologic state, and demonstrates its validity through simulations and an Alzheimer's disease study.