Matt J. Neville

The paper characterizes genetic determinants of context-specific DNA methylation in primary monocytes exposed to inflammatory stimuli, identifying 209 CpGs under genetic control and linking them to disease.

This study identifies 400+ genetic loci associated with circulating metabolic traits and highlights pleiotropy and novel disease pathways.

This paper improves genetic scores for adiposity traits in East Asian populations by using trans-ancestry meta-analysis, increasing variance explained compared to European-derived scores.

The paper identifies an association between the HLA-DQA1*01:03 allele and increased risk of invasive group A streptococcal disease using case-control studies and HLA imputation.

This study identifies genetic variants associated with specific fat depot masses using exome-wide analysis in large cohorts, revealing distinct genetic regulation of different fat depots.

The paper identifies low-frequency coding variants contributing to multiple sclerosis risk using a large case-control study.