Author

Peter G. Mikhael

Duke UniversityORCID 0000-0002-6030-1636Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jason W. LocasaleiD· 2 shared Sydney M. SandersoniD· 2 shared Ziwei DaiiD· 2 shared Amy Ciccarella· 1 shared Ana Calcagnotto· 1 shared Catherine Van DongeniD· 1 shared Daniel E. Cooper· 1 shared David G. KirschiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Jason W. LocasaleORCID

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3 papers

Recent·Most cited

BiochemistrySciencePeer-reviewedFeb 6, 2025

Protein codes promote selective subcellular compartmentalization

Henry R. Kilgore, Itamar Chinn, Peter G. Mikhael…·Richard A. Young

This study introduces ProtGPS, a protein language model that predicts subcellular compartment localization and identifies mutations affecting this process.

105 citationstop 1%

humanprotein sequence

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Cancer BiologybioRxivPreprintMay 4, 2019

Dietary methionine restriction targets one carbon metabolism in humans and produces broad therapeutic responses in cancer

Xia Gao, Sydney M. Sanderson, Ziwei Dai…·Jason W. Locasale

This study shows that dietary methionine restriction affects one carbon metabolism in humans and produces therapeutic responses in cancer by altering metabolic pathways.

DOI 10.1101/627364

humanmouse

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Molecular BiologybioRxivPreprintMay 2, 2018

Environmental factors shape methionine metabolism in p16/MTAP deleted cells

Sydney M. Sanderson, Peter G. Mikhael, Ziwei Dai, Jason W. Locasale

This study shows that environmental factors like nutrition and tissue type have a greater impact on methionine metabolism in p16/MTAP deleted cells than the genetic deletion itself.

1 citation

humanmetabolomics

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