Author

Iga Niemiec

University of HelsinkiORCID 0000-0002-6134-5083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:spatial transcriptomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:machine learning (classical)· 2

Frequent Co-Authors

Anna VähärautioiD· 3 shared Anni VirtaneniD· 3 shared Anniina FärkkiläiD· 3 shared Matilda SalkoiD· 3 shared Ada JunqueraiD· 2 shared Ashwini Sakrepatna NagarajiD· 2 shared Erdoğan Pekcan ErkaniD· 2 shared Essi KaheliniD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Anna VähärautioORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedFeb 9, 2026

✦ In-depth digest

Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes

Fernando Pérez‐Villatoro, Aleksandra Shabanova, Lilian van Wagensveld…·Anniina Färkkilä

Cyclic immunofluorescence of 265 high-grade serous ovarian carcinomas and random-forest feature ranking identify cancer-cell MHC-II as an adjusted predictor of longer survival marking immune-activated tumor-stroma hotspots.

10 citationstop 1%

humanimaging

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Cancer BiologyCancer CellPeer-reviewedDec 1, 2024

Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer

Inga-Maria P. Launonen, Iga Niemiec, María Mercedes Hincapié-Otero…·Anniina Färkkilä

This study shows chemotherapy causes myeloid-driven spatial T-cell exhaustion in ovarian cancer by altering immune cell states and interactions, suggesting new immunotherapy approaches.

103 citationstop 1%

humanscRNA-seq

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Cancer BiologybioRxivPreprintFeb 15, 2024

Patient-derived functional immuno-oncology platform identifies responders to ATR inhibitor and immunotherapy combinations in ovarian cancer

Ashwini Sakrepatna Nagaraj, Matilda Salko, Aditi Sirsikar…·Anniina Färkkilä

4 citations

humanbulk RNA-seq

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BioinformaticsFrontiers in GeneticsPeer-reviewedMar 25, 2021

AI aided design of epitope-based vaccine for the induction of cellular immune responses against SARS-CoV-2

Giovanni Mazzocco, Iga Niemiec, Alexander Myronov…·Piotr Stępniak

This paper uses AI and bioinformatics to design epitope-based vaccines for cellular immunity against SARS-CoV-2, evaluating immunogenicity and safety risks.

23 citations

machine learning (classical)drug response / drug discovery

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