Author

Stephen E. Hamby

University of LeicesterORCID 0000-0002-6215-5791Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

Adrien B. GeorgesiD· 2 shared Anna BaranowskaiD· 2 shared Daniella L. Kadian‐DodoviD· 2 shared David AdlamiD· 2 shared Jason Ciril KovaciciD· 2 shared Jeffrey W. OliniD· 2 shared Min‐Lee YangiD· 2 shared Nabila Bouatia‐NajiiD· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Adrien B. GeorgesORCID

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3 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedApr 1, 2024

Ageing-related defects in macrophage function are driven by MYC and USF1 transcriptional programmes

Charlotte E. Moss, Simon Andrew Johnston, Joshua V. Kimble…·Endre Kiss‐Toth

This study identifies MYC and USF1 as key drivers of age-related functional decline in human macrophages, showing their role in phagocytosis, migration, and morphology.

80 citationstop 1%

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintJul 5, 2022

Genome-wide association meta-analysis of spontaneous coronary artery dissection reveals common variants and genes related to artery integrity and tissue-mediated coagulation

David Adlam, Takiy-Eddine Berrandou, Adrien B. Georges…·Nabila Bouatia‐Naji

This study identifies 17 genetic risk loci for spontaneous coronary artery dissection (SCAD), including 12 new ones, and highlights genes related to artery integrity and coagulation.

5 citations

humanGWAS summary statistics

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Genetic & Genomic MedicineCardiovascular ResearchPeer-reviewedJun 7, 2020

Rare Loss-of-Function Mutations of PTGIR identified in Fibromuscular Dysplasia and Spontaneous Coronary Artery Dissection

Adrien B. Georges, Juliette Albuisson, Takiy-Eddine Berrandou…·Nabila Bouatia‐Naji

The paper identifies rare loss-of-function mutations in PTGIR in FMD and SCAD patients, showing impaired prostacyclin receptor function and suggesting a role for prostacyclin signaling in these diseases.

33 citations

humanwhole-exome sequencing

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