Author

Hazal Koptagel

Science for Life LaboratoryORCID 0000-0002-6234-4656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

Jens LagergreniD· 2 shared Andrew J. L. RothiD· 1 shared Camila P. E. de SouzaiD· 1 shared Hosein ToosiiD· 1 shared Joanna HårdiD· 1 shared Negar SafinianainiiD· 1 shared Seong-Hwan JuniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBioinformatics

Jens LagergrenORCID

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2 papers

Recent·Most cited

BioinformaticsComputational Biology and ChemistryPeer-reviewedOct 23, 2024

CopyMix: Mixture Model Based Single-Cell Clustering and Copy Number Profiling using Variational Inference

Negar Safinianaini, Camila P. E. de Souza, Andrew J. L. Roth…·Jens Lagergren

CopyMix jointly infers cell clusters and copy number profiles from single-cell DNA sequencing data, avoiding clustering artifacts and parameter tuning.

3 citations

humanscRNA-seq

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedMay 9, 2024

Scuphr: A probabilistic framework for cell lineage tree reconstruction

Hazal Koptagel, Seong-Hwan Jun, Joanna Hård, Jens Lagergren

Scuphr reconstructs cell lineage trees using bulk and single-cell DNA sequencing data, addressing technical artifacts and improving accuracy over existing methods.

8 citations

whole-genome sequencingbulk RNA-seq

𝕏 PostBluesky