Author

Karen Zagorski

Nebraska Medical CenterORCID 0000-0002-6236-0808Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Mohtadin HashemiiD· 2 shared Siddhartha BanerjeeiD· 2 shared Yuri L. LyubchenkoiD· 2 shared Jean‐Christophe RochetiD· 1 shared Zhengjian Lv· 1 shared

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2019-2020 · peak 1/yr

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2 shared papersNeuroscience

Mohtadin HashemiORCID

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2 papers

Recent·Most cited

NeuroscienceInternational Journal of Molecular SciencesPeer-reviewedFeb 8, 2020

Lipid membranes trigger misfolding and self-assembly of amyloid β 42 protein into aggregates

Siddhartha Banerjee, Mohtadin Hashemi, Karen Zagorski, Yuri L. Lyubchenko

The paper shows that Aβ42 monomers at lipid membranes self-assemble into aggregates at low concentrations, with the membrane acting as a catalyst.

49 citations

experimental assay

𝕏 PostBluesky

NeuroscienceBiochimica et Biophysica Acta (BBA) - Proteins and ProteomicsPeer-reviewedJun 18, 2019

Phospholipid membranes promote the early stage assembly of α-synuclein aggregates

Zhengjian Lv, Mohtadin Hashemi, Siddhartha Banerjee…·Yuri L. Lyubchenko

This study shows phospholipid bilayers catalyze α-synuclein aggregation from monomers, with efficiency depending on membrane composition and leading to dissociable aggregates.

51 citationstop 4%

experimental assay

𝕏 PostBluesky