GeneticsG3 Genes Genomes GeneticsPeer-reviewed
Population selection and sequencing of C. elegans wild isolates identifies a region on chromosome III affecting starvation resistance
23 citations
Author
Rebecca E. W. Kaplan
Duke UniversityORCID 0000-0002-6237-1435Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2019 · peak 5/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
- GeneticsGeneticsPeer-reviewed
Pervasive positive and negative feedback regulation of insulin like signaling in Caenorhabditis elegans
Colin S. Maxwell, Rebecca E. W. Kaplan, Nicole A. Kurhanewicz, L. Ryan Baugh
The paper investigates feedback regulation in the C. elegans insulin-like signaling network during state transitions, revealing widespread positive and negative feedback mechanisms.
22 citations - Developmental BiologyCell ReportsPeer-reviewed
Ral signals through a MAP4 Kinase-p38 MAP kinase cascade in C. elegans cell fate patterning.
Hanna Shin, Rebecca E. W. Kaplan, Tam Duong…·David J. Reiner
The paper identifies a Ral-dependent signaling cascade in C. elegans that transduces lower EGF doses to promote 2° vulval precursor cell fate.
22 citations - GeneticsbioRxivPreprint
Developmental fidelity imposed by the RGL-1 balanced switch mediating opposing signals
Hanna Shin, Christian Braendle, Kimberly B. Monahan…·David J. Reiner
This study identifies RGL-1 as a balanced switch that coordinates opposing signals to ensure developmental fidelity in C. elegans vulval precursor cells.
DOI 10.1101/381012 - Developmental BiologybioRxivPreprint
Intergenerational effects of dietary restriction on insulin/IGF signaling and reproductive development
James M. Jordan, Jonathan D. Hibshman, Rebecca E. W. Kaplan…·L. Ryan Baugh
This study investigates how maternal dietary restriction affects reproductive development in C. elegans by modulating insulin/IGF signaling, reducing starvation-induced abnormalities in progeny.
DOI 10.1101/342956 - Developmental BiologybioRxivPreprint
Perception of environmental polypeptides in C. elegans activates insulin/IGF signaling and alters lipid metabolism
Rebecca E. W. Kaplan, Amy K. Webster, Rojin Chitrakar…·L. Ryan Baugh
The paper shows that food perception in C. elegans activates insulin/IGF signaling and alters lipid metabolism, but this response is harmful if feeding does not occur.
DOI 10.1101/341883