BioinformaticsPLoS ONEPeer-reviewed
Testing an Optimally Weighted Combination of Common and/or Rare Variants with Multiple Traits
Zhenchuan Wang, Qiuying Sha, Shurong Fang…·Shuanglin Zhang
This paper introduces TOWmuT, a statistical method for testing associations between multiple traits and a weighted combination of genetic variants, showing it is more powerful than existing methods.