Mengting Han

This paper creates a super-resolution atlas of SARS-CoV-2 infection, revealing protease-dependent organelle maturation, dsRNA structures, and structural proteins, with implications for antiviral strategies.

This study demonstrates a programmable macromolecule delivery system using engineered trogocytosis to transfer proteins between cells, enabling genome editing and targeted cell ablation.

This study introduces CRISPR-TO to manipulate RNA localization in neurons, showing it affects neurite outgrowth and axonal regeneration.

This study uses super-resolution microscopy to reveal the nanoscale organization of SARS-CoV-2 replication organelles, showing distinct vgRNA and dsRNA clusters and changes over infection stages.

This study uses CRISPR-EChO to investigate HP1's role in organizing chromatin at supranucleosomal scales, revealing its ability to compact chromatin and repress transcription over large genomic regions.