Author

Helian Feng

Harvard UniversityORCID 0000-0002-6296-1902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:GWAS / association mapping· 1 Approach:statistical model· 1

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Alexander GuseviD· 1 shared Arunabha MajumdariD· 1 shared Bogdan PaşaniuciD· 1 shared Megan MajoriD· 1 shared Nicholas MancusoiD· 1 shared Peter KraftiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperGenetics

Alexander GusevORCID

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1 paper

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedApr 8, 2021

Leveraging expression from multiple tissues using sparse canonical correlation analysis (sCCA) and aggregate tests improves the power of transcriptome-wide association studies (TWAS)

Helian Feng, Nicholas Mancuso, Alexander Gusev…·Peter Kraft

This paper improves transcriptome-wide association study (TWAS) power by integrating multiple tissues using sparse canonical correlation analysis (sCCA) and aggregate tests, identifying more gene-trait associations.

97 citationstop 2%

bulk RNA-seqstatistical model

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