Author
University of LeedsORCID 0000-0002-6328-7200Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Safia Aljedani, Anandsukeerthi Sandholu, Abdullah Aldehaiman…·Stefan T. Arold
This study identifies how SH3 domains activate PI3K by engaging in tertiary interactions with p85, revealing a mechanism for controlling activation through functional selection.
Christopher Mark Jones, Arndt Rohwedder, Kin Man Suen…·John Edward Ladbury
The paper identifies 490 interactors of RTK PRM regions using affinity purification mass spectrometry, revealing overrepresented metabolic and migratory functions in cancer cells.
Molly R. Patterson, Aniek S. Meijers, Emma L. Ryder…·Andrew Macdonald
This study shows that HPV E7 represses miR-203, leading to LASP1 upregulation and promoting proliferation in HPV-positive cervical cancer.
Rowan D. Taylor, James A. Poulter, Joseph J. B. Cockburn…·Colin A. Johnson
This study investigates how alternative splicing, specifically nonsense-associated altered splicing (NAS), affects the pathogenesis of CEP290-related ciliopathies by analyzing splicing patterns and ciliogenesis in induced pluripotent stem cells.