Author

Ashley M. Holt

Texas A&M University SystemORCID 0000-0002-6365-7144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Chandler O’LearyiD· 1 shared Christina M. HulliD· 1 shared Cody MartiniD· 1 shared Jacqueline A SpielesiD· 1 shared Jeniel E. NettiD· 1 shared Jesse L. CahilliD· 1 shared Jie XiaoiD· 1 shared Kelsey E. BettridgeiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Chandler O’LearyORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 16, 2026

Inhibitors of spore germination act against diverse human fungal pathogens

Jacqueline A Spieles, Seth D. Greengo, Ashley M. Holt…·Christina M. Hull

The paper evaluates 191 small molecule inhibitors of Cryptococcus germination for their activity against other fungal pathogens and human cell toxicity, identifying 101 with therapeutic potential.

DOI 10.64898/2026.09.15.751812

humanexperimental assay

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedDec 21, 2023

Spatial and temporal control of lysis by the lambda holin

Jesse L. Cahill, Ashley M. Holt, Matthew Theodore…·Ry Young

The paper investigates the molecular basis of polar lysis in phage λ using time lapse fluorescence microscopy, finding that the holin forms two-dimensional rafts at cell poles before lysis.

25 citations

bacteria (other)fluorescence / live-cell microscopy

𝕏 PostBluesky