Ho Cheung Shum

The paper identifies an entropic charge separation mechanism that limits coarsening in nanoscale condensates, explaining their long-term stability.

This study shows ATP forms protein-free condensates in crowded environments, which are responsive to stimuli and protect RNA from cleavage.

This paper demonstrates that coacervate droplets can reverse solid RNA-peptide aggregates into functional liquid droplets, offering a method to manage pathological aggregation.

This study investigates ATP condensate aging, revealing liquid-to-solid phase transitions and dynamic behaviors like dialytaxis and internal flows driven by the Marangoni effect.

The paper shows that a single sugar difference between DNA and RNA drives phase segregation with cationic peptides, enabling programmable synthetic condensates that mimic nuclear compartments.

This study investigates how alcohol-induced phase transitions in biomolecular condensates depend on sidechain chemistry and molecular interactions, revealing mechanisms for liquid-to-solid and solid-to-liquid transitions.

This paper describes a method to create monodisperse complex droplets that mimic extremophiles by using coacervate-liposome interactions.