Sven Hammerschmidt

The paper identifies HERC4 as a regulator of ROS-induced DNA damage during bacterial and viral-bacterial infections, showing its role in DNA repair and potential as a therapeutic target.

This study shows that 25-hydroxycholesterol protects against pneumolysin-induced vascular injury, while its suppression allows bacterial containment through coagulation, with PAF acting as a compensatory antagonist.

PneumoWiki is a pan-genome database for Streptococcus pneumoniae that integrates genomic data and functional annotations across 43 strains to support research and data analysis.

This study uses proteomics and independent component analysis to show ClpX regulates S. aureus responses to iron and oxygen limitation and affects bacterial fitness and virulence.

This study optimizes a nutrient-defined medium for Streptococcus pneumoniae and uses it to analyze the global proteome during growth phase transitions, identifying proteins with altered abundance in late log phase.

This study presents structural analysis of the Ami transporter system in Streptococcus pneumoniae, revealing insights into oligopeptide recognition and transport mechanisms.

The paper investigates how atypical N-glycosylation of SARS-CoV-2's spike protein affects its binding to hACE2, revealing structural and functional implications for viral transmission.