David Pitt

The paper pairs miRNA and mRNA profiles from circulating sEVs to identify survival-associated programs in ALS, finding a five-miRNA panel and a five-gene core linked to glial and vascular responses.

AutoMorFi automates whole-image morphometric analysis, generating over 47 measurements per cell quickly and enabling new discoveries across diverse biological samples.

The paper compares TIGIT expression in glioblastoma tumor-infiltrating T cells and multiple sclerosis lesions, finding higher TIGIT expression in GBM and suggesting anti-TIGIT therapy as a potential treatment.

The paper shows that the MS risk variant rs7665090G increases astrocyte NF-κB signaling and lymphocyte recruitment, leading to larger MS lesions.