Laura K. Hilton

This study identifies a thymus-specific B-cell differentiation program linked to thymic B-cell lymphomagenesis through single-cell multiomics and spatial profiling.

The paper establishes a PDX repository of large B-cell lymphoma models capturing clinical and molecular diversity, including post-CART19 progression cases.

LCR-modules provides a flexible, automated suite of workflows for cancer genome analysis, supporting diverse sequencing types and enabling reproducible, scalable analysis of over 10,800 samples.

This study identifies four molecular subtypes of Hodgkin lymphoma using multimodal data, revealing distinct clinical features and immune ecosystem dynamics.

This paper introduces a self-training method for gene expression-based cancer classification that works across different data types and normalization methods.

This study identifies somatic coding and regulatory variants in DLBCL, revealing novel mechanisms of oncogene deregulation and potential therapeutic targets.