Author

Alan O. Gao

University of CopenhagenORCID 0000-0002-6446-4889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Irene GallinaiD· 1 shared Johannes C. WalteriD· 1 shared Julien P. DuxiniD· 1 shared Justin L. Sparks· 1 shared Markus RäschleiD· 1 shared Matthias ManniD· 1 shared Nicolai Balle LarseniD· 1 shared

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2018-2018 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Irene GallinaORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintAug 1, 2018

Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

Alan O. Gao, Nicolai Balle Larsen, Justin L. Sparks…·Julien P. Duxin

This study shows that both SPRTN and the proteasome degrade DNA-protein crosslinks during DNA replication, using distinct mechanisms involving ubiquitylation and polymerase extension.

2 citations

experimental assay

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