MicrobiologybioRxivPreprint
Fatty acid synthesis restricts HIV-1 infection through regulation of the nuclear envelope in CD4+ T cells
Joshua A. Acklin, Ming Ye, Erika A. Pontillo…·Alison Epstein Ringel
DOI 10.64898/2026.09.22.753563
Author
Alison Epstein Ringel
Ragon Institute of MGH, MIT and HarvardORCID 0000-0002-6451-9376Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- MicrobiologymSpherePeer-reviewed
Systems analysis reveals alternate metabolic states adopted by Mycobacterium tuberculosis across species
Jonathan Padilla‐Gómez, Rachel A. McGinn, Victoria Andrade…·Bryan D. Bryson
This study compares the metabolic states of Mycobacterium tuberculosis in human and mouse macrophages, revealing species-specific lipid metabolism and identifying a barrier to lipid access in human macrophages.
- ImmunologybioRxivPreprint
Citrate Compartmentalization Controls Calcium-Dependent Cytokine Production in Effector T Cells
Andrea L Cote, Claire McIntyre, Joshua A. Acklin…·Alison Epstein Ringel
This study shows that citrate compartmentalization regulates calcium-dependent cytokine production in effector T cells by linking glucose availability to calcium signaling.
DOI 10.64898/2026.06.11.731694 - Cell BiologybioRxivPreprint
MARBL: A Live-Cell Method for Profiling Bioenergetic Heterogeneity by Noncanonical Methionine Labeling of the Cell Surface Proteome
Lillian R. Delacruz, Ming Ye, Kendra A. Libby…·Alison Epstein Ringel
MARBL profiles bioenergetic heterogeneity in live cells by noncanonical methionine labeling of the surface proteome, revealing metabolic resilience differences between immune cell types.
DOI 10.64898/2026.06.01.729353 - ImmunologyCellPeer-reviewed
PPARγ downregulation in colonic CD8+ T cells results in epithelial barrier disruption in people with HIV on antiretroviral therapy
Upasana Das Adhikari, Leah M. Froehle, Alexandra N. Pipkin…·Douglas S. Kwon
This study shows that PPARγ downregulation in colonic CD8+ T cells of people with HIV on ART leads to epithelial barrier disruption by promoting lipid uptake and apoptosis.
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