Author

Jack Feltham

University of OxfordORCID 0000-0002-6461-7355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Jane MelloriD· 2 shared Andrew AngeliD· 1 shared Anna F. Townley· 1 shared Anna Katharina SimoniD· 1 shared Benedikt Mathias KessleriD· 1 shared Charlotte L. GeorgeiD· 1 shared Emile RobertsiD· 1 shared Ghada AlsalehiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Jane MellorORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 10, 2020

Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels

Jack Feltham, Shidong Xi, Struan C. Murray…·Jane Mellor

The paper shows that transcriptional changes during biological rhythms do not directly affect protein levels, which remain constant due to slow turnover rates and post-translational regulation.

9 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

Cell BiologybioRxivPreprintDec 12, 2018

Translational control of TFEB and autophagy via eIF5A rejuvenates B cell immunity

Hanlin Zhang, Ghada Alsaleh, Jack Feltham…·Anna Katharina Simon

This study identifies a mechanism by which spermidine regulates autophagy through eIF5A-mediated TFEB translation, improving B cell immunity in aging.

DOI 10.1101/360503

humanmouse

𝕏 PostBluesky