Author
New York Structural Biology CenterORCID 0000-0002-6471-4243Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Samantha Zangari, Madeline E. Sherlock, Jeffrey S. Kieft
The paper identifies conserved structural features of PV1 ciRNA that inhibit RNase L and shows limited phylogenetic distribution of functional ciRNAs within Enterovirus coxsackiepol.
Elizabeth Spear, Zoe O’Donoghue, Steve L. Bonilla…·Jeffrey S. Kieft
This paper identifies an A-rich linker between tandem xrRNAs in DENV2 that stabilizes their structural coupling, influencing sfRNA patterns and viral fitness.
Katherine Elizabeth Segar, Madeline E. Sherlock, Jeffrey S. Kieft
The paper identifies and classifies 163 putative Type IV IRESs from diverse viruses, revealing structural variations that correlate with functional differences.
Conner J. Langeberg, Matthew J. Szucs, Madeline E. Sherlock…·Jeffrey S. Kieft
The paper identifies and characterizes a novel 'double loop' structure in tick-borne flavivirus xrRNAs, revealing a conserved mechanism of exoribonuclease resistance.
Madeline E. Sherlock, Katherine E. Segar, Jeffrey S. Kieft
The paper identifies a compact Type IV IRES in the 3' UTR of megrivirus E, confirms its structure, and shows it enables translation of a downstream open reading frame with reduced activity compared to the 5' UTR IRES.
Madeline E. Sherlock, Conner J. Langeberg, Katherine E. Segar, Jeffrey S. Kieft
The paper identifies and characterizes viral RNA structures that regulate translation reinitiation through ribosome interactions, revealing conserved features and dynamic conformations.