Author

Ali Sinan Saglam

University of PittsburghORCID 0000-0002-6513-8401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:software / tool· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

James R. FaederiD· 3 shared Aarthi NarayananiD· 1 shared Adrianne L. JenneriD· 1 shared Amber M. SmithiD· 1 shared Andrew BeckeriD· 1 shared Ashlee N. Ford VersyptiD· 1 shared Bing LiuiD· 1 shared Caroline I. LarkiniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

James R. FaederORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 28, 2022

WEBNG: A templating tool for weighted ensemble sampling of rule-based models

Ali Sinan Saglam, James R. Faeder

WEBNG simplifies rare event sampling in rule-based models by integrating BioNetGen and WESTPA, enabling efficient simulation with default parameters.

1 citation

experimental assaysoftware / tool

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedDec 28, 2021

Combination Treatment Optimization Using aPan-Cancer Pathway Model

Robin Schmucker, Gabriele Farina, James R. Faeder…·Tüomas Sandholm

This paper uses a pan-cancer pathway model to identify novel combination therapies and optimize treatment sequences for cancer cell lines.

17 citations

statistical modeldrug response / drug discovery

𝕏 PostBluesky

Systems BiologybioRxivPreprintApr 2, 2020

✦ In-depth digest

Iterative community-driven development of a SARS-CoV-2 tissue simulator

Michael Getz, Yafei Wang, Gary C. An…·Paul Macklin

Open-source agent-based PhysiCell model of SARS-CoV-2 infection in lung epithelium; version 5 clears virus in about 6 days in simulation, and delayed T cell arrival increases epithelial loss.

61 citations

𝕏 PostBluesky