Ànna Pavlova

This study identifies modified crRNA variants for precise targeting of point mutations in human mitochondrial DNA using CRISPR-Cas12a, showing effective discrimination and base editing in vitro and in human cells.

The paper identifies ligands that bind beyond a known hydrophobic pocket at the HBV core protein interface using molecular dynamics and fragment mapping.

This study investigates the biogenesis of the SARS-CoV-2 M protein, revealing key steps in its insertion, folding, and oligomerization.

The paper investigates how spatial separation of antigens affects cytotoxicity in CAR-TCR cells by analyzing clonotype dynamics and functional TCR contributions.

This paper uses machine learning to classify molecular dynamics simulations of viral capsid assembly intermediates, distinguishing between apo and CAM-bound states with high accuracy.

This study investigates how mRNA structures affect ribosome intersubunit rotation using smFRET and MD simulations.