Author

Yuesong Hu

Emory UniversityORCID 0000-0002-6528-0491Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Jhordan RogersiD· 2 shared Khalid S. SalaitaiD· 2 shared Alexander K. Foote· 1 shared Arventh VelusamyiD· 1 shared Rong MaiD· 1 shared Sarah Al AbdullatifiD· 1 shared Steven M. NarumiD· 1 shared Yuxin DuaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

Jhordan RogersORCID

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2 papers

Recent·Most cited

BiophysicsNature NanotechnologyPeer-reviewedAug 5, 2024

DNA Origami Tension Sensors (DOTS) to study T cell receptor mechanics at membrane junctions

Yuesong Hu, Jhordan Rogers, Yuxin Duan…·Khalid S. Salaita

This study develops DNA origami tension sensors (DOTS) to measure TCR mechanotransduction at immune cell junctions, revealing forces between 5-10 pN and dependencies on cell state and antigen properties.

68 citationstop 1%

humanexperimental assay

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BiophysicsJournal of the American Chemical SocietyPeer-reviewedMar 7, 2024

Force-induced site-specific enzymatic cleavage probes reveal that serial mechanical engagement boosts T cell activation

Jhordan Rogers, Rong Ma, Alexander K. Foote…·Khalid S. Salaita

This paper introduces FUSE probes to study how force duration affects T cell activation, finding that repeated mechanical engagement boosts activation, especially at lower antigen densities.

16 citations

humanproteomics

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