Jaspreet Singh

The paper generates iPSC-derived astrocytes from AMN and cALD patients to model X-ALD phenotypes and study disease mechanisms.

This study uses iPSC-derived astrocytes to compare metabolic and inflammatory responses between AMN and cALD phenotypes in X-ALD, identifying miR-9 as associated with disease severity.

The paper identifies altered metabolic pathways in RRMS patients using metabolomics and shows that targeting glycolysis can reduce disease progression in a mouse model.