Janine N. Post

The paper maps chondrogenic cell-fate trajectories in hiPSCs using scRNA-seq and scATAC-seq, identifying NFIA and NFIB as key regulators driving chondrogenic commitment.

DANSE models time-series multi-omics data to identify key transcription factors driving biological processes, using iPSC differentiation datasets as examples.

The paper develops a Boolean gene regulatory network model to simulate cardiomyocyte differentiation into ventricular or atrial types, validated by reproducing known knockouts and aligning with marker gene expression.

The paper investigates SOX9 transcriptional dynamics in human mesenchymal stem cells during differentiation into chondrogenic, osteogenic, and adipogenic lineages, revealing subpopulations and donor-specific differences.