Chad M. Swanson

This study shows that m6A RNA modifications regulate antiviral gene expression by limiting IFITM2/3 expression during influenza A virus infection.

This study identifies how the long ZAP isoform recruits enzymes to degrade viral RNA through a coordinated decay pathway.

This study characterizes the KHNYN ex-diKH domain's role in ZAP antiviral activity, revealing its structural features and identifying a potential protein-protein interaction site.

The paper evaluates bioinformatics tools for detecting human endogenous retroviral insertions in short-read genome sequencing data, finding performance variability across datasets and recommending a consensus approach.

RetroSnake detects HERVs in NGS data using an end-to-end pipeline validated by wet-lab experiments, producing annotated insertions in an interactive HTML file.

The paper identifies KHNYN as a novel ZAP cofactor essential for restricting HIV-1 with clustered CpG dinucleotides.